Universidade do Estado de Santa Catarina (often abbreviated UDESC) is a university in Brazil. Its name in English is Santa Catarina State University, although it is commonly called UDESC, its acronym. It was established in 1965.

UDESC is located in Santa Catarina state in southern Brazil, primarily in Florianópolis, but it has multiple campuses in 10 cities. According to its official website, it has over 13,000 students.

UDESC boasts a wide variety of academic areas of concentration, both scientific and artistic.

Its Arts division (Centro de Artes) is known by the abbreviation CEART. Subdivisions of study there are primarily in: performing arts, visual arts, design, fashion, and music.

Academic production